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Broadly Neutralizing Human Anti-HIV Antibody 2G12 Is Effective in Protection against Mucosal SHIV Challenge Even at Low Serum Neutralizing Titers

  • Ann J. Hessell,

    Affiliation Department of Immunology and Microbial Science, and IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America

  • Eva G. Rakasz,

    Affiliation Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

  • Pascal Poignard,

    Affiliations Department of Immunology and Microbial Science, and IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America, International AIDS Vaccine Initiative (IAVI), New York, New York, United States of America

  • Lars Hangartner,

    Affiliations Department of Immunology and Microbial Science, and IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America, Institute of Medical Virology, University of Zürich, Zürich, Switzerland

  • Gary Landucci,

    Affiliation Division of Infectious Diseases, Department of Medicine, UC Irvine School of Medicine, University of California Irvine, Irvine, California, United States of America

  • Donald N. Forthal,

    Affiliation Division of Infectious Diseases, Department of Medicine, UC Irvine School of Medicine, University of California Irvine, Irvine, California, United States of America

  • Wayne C. Koff,

    Affiliation International AIDS Vaccine Initiative (IAVI), New York, New York, United States of America

  • David I. Watkins,

    Affiliation Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

  • Dennis R. Burton

    burton@scripps.edu

    Affiliation Department of Immunology and Microbial Science, and IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America

Broadly Neutralizing Human Anti-HIV Antibody 2G12 Is Effective in Protection against Mucosal SHIV Challenge Even at Low Serum Neutralizing Titers

  • Ann J. Hessell, 
  • Eva G. Rakasz, 
  • Pascal Poignard, 
  • Lars Hangartner, 
  • Gary Landucci, 
  • Donald N. Forthal, 
  • Wayne C. Koff, 
  • David I. Watkins, 
  • Dennis R. Burton
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