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Beta HPV38 oncoproteins act with a hit-and-run mechanism in ultraviolet radiation-induced skin carcinogenesis in mice

Fig 5

Luciferase expression vectors can be efficiently electroporated into skin lesions of K14 HPV38 E6/E7 Tg mice.

(A) Schematic diagram of the electroporation procedure of skin lesions of K14 HPV38 E6/E7 Tg mice. (B) Luciferase activity is detected in lesions electroporated with the control vector (Luc) as well as in lesions electroporated with the plasmid coding for the Cre recombinase and luciferase genes (CRE-Luc). Mice and tumour growth are closely monitored at regular intervals.

Fig 5

doi: https://doi.org/10.1371/journal.ppat.1006783.g005