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Three mutations switch H7N9 influenza to human-type receptor specificity

Fig 6

Modeling of bidendate binding for biantennary tri-LacNAc N-glycans to WT and V186K, K193T G228S triple mutant (TM) H7.

The 6’SLN3-N glycan was impeded by K193 in the WT (A), but was able to span two binding sites in the TM H7 (B).

Fig 6

doi: https://doi.org/10.1371/journal.ppat.1006390.g006