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Three mutations switch H7N9 influenza to human-type receptor specificity

Fig 5

Melting curve of recombinant HA obtained by DSC to determine the thermostability of Sh2, Sh2 V186K K193T G228S, and A/KY/07.

The raw data are depicted in the solid line, while the fitted curve, from which the Tm was derived, is depicted with a dotted line. (A) A summary of the peaks observed during the DSC experiments for each recombinant HA, (B) Sh2, (C) A/KY/07 and (D) Sh2 V186K K193T G228S.

Fig 5

doi: https://doi.org/10.1371/journal.ppat.1006390.g005