Discovery of a Natural Microsporidian Pathogen with a Broad Tissue Tropism in Caenorhabditis elegans
(a) Phylogenomic tree of N. displodere and 18 other microsporidia genomes, with Rozella allomycis as an outgroup. Bootstrap support is indicated next to each node. Scale bar indicates changes per site. The tree was created with FigTree 1.4.2 (http://tree.bio.ed.ac.uk/software/figtree/). (b) Histogram of intergenic region lengths of the three Nematocida species. (c) Comparison of protein content among the three Nematocida species. Proteins were classified into 7 categories: proteins shared with all Nematocida and at least 1 other non-microsporidian eukaryotic species (eukaryotic), proteins shared between all Nematocida and at least 1 other microsporidian species (microsporidia), proteins shared only between all the three Nematocida species (Nematocida), proteins shared by N. displodere and N. parisii, proteins shared by N. displodere and N. sp. 1, proteins shared by N. parisii and N. sp. 1, and proteins not in any other species (unique). (d) Protein schematic of a generalized member of each of the large gene families in the Nematocida species, which contain signal peptides (SP). The average size of the gene family and the number of proteins in each species are indicated at the right.