Discovery of a Natural Microsporidian Pathogen with a Broad Tissue Tropism in Caenorhabditis elegans
(a) Cross-section of an uninfected adult with the epidermis (Ep) and intestine (In) shown, separated by the pseudocoelom (Pc). The intestinal lumen (Lu) is indicated. (b) Cross-section of an N. displodere-infected adult at 6 dpi with large multinucleate meronts (Me) presumably in the epidermis, adjacent to two flanks of the body wall muscle (Mu). (c) Large associated cluster of N. displodere sporonts with nascent polar tube coils (PT) in an infected animal at 8 dpi. (d-e) Groups of nascent spores, presumably sporoblasts, in an 8 dpi animal. (f-g) Longitudinal and cross-sectional views of spores in an 8 dpi animal, with five polar tube coils. Scale bars are 1 μm (a-d) and 0.5 μm (e-g).