Influenza Virus Reassortment Is Enhanced by Semi-infectious Particles but Can Be Suppressed by Defective Interfering Particles
Fig 1
Relationships between % infection and % reassortment or % co-infection, as predicted by computational simulation of co-infection with viruses of two types.
Viruses of type A and type B were assigned at random to a computational set of cells over a range of MOIs. Cells infected with any virus type were counted as infected and cells infected with both A and B types were counted as co-infected. The proportion of progeny viruses carrying a reassortant genome produced from each infected cell was calculated, taking into account the number type A and type B viruses present in each cell. The average % reassortment for all infected cells is plotted.