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Inhibition and Reversal of Microbial Attachment by an Antibody with Parasteric Activity against the FimH Adhesin of Uropathogenic E. coli

Fig 1

Inhibitory potency of mAb926 and mAb475.

Binding of FimH^wt-expressing E. coli to surface-immobilized yeast mannan in the presence of different concentrations of anti-FimH antibodies. Data are mean ± SEM (n = 5 independent experiments). The IC₅₀ values were calculated from the fitted curves shown using Prism GraphPad 6 software. **, P ≤ 0.005 (t-test).

doi: https://doi.org/10.1371/journal.ppat.1004857.g001