Uropathogenic Escherichia coli Superinfection Enhances the Severity of Mouse Bladder Infection
Figure 4
UTI89 Superinfection of C57BL/6J mice increases bladder and kidney infection.
A–B) mice were infected with PBS or UTI89 Kanr and re-infected 24 hrs later with PBS or UTI89 Spectr. Urine was tracked over four weeks and total bladder (A) and kidney pair titer (B) is displayed. Number above columns indicates number of mice with persistent bacteriuria with bladder (A) or kidney (B) titer>104 CFU. Data represents 3–8 experiments with n = 4–29 mice per group. Panels also include data reproduced from Fig. 3. Statistical differences determined by Fisher's Exact test.