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Dynamics of HIV Latency and Reactivation in a Primary CD4+ T Cell Model

Figure 2

Dynamics of HIV latency in a primary CD4+ T cell model.

Viral-encoded GFP expression (green) and activation marker IL2Rα (CD25) expression (black) during the steps of entry into latency (week -3 to week 2), maintenance of latency (week 4 to 10), and reactivation upon TCR stimulation (8, 24, and 72 hours after week 10). Shown are the geometric mean fluorescence of intensity (geoMFI) ratios of HIV-based vector infected cells and mock non-infected control cells.

Figure 2

doi: https://doi.org/10.1371/journal.ppat.1004156.g002