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Red Blood Cell Invasion by Plasmodium vivax: Structural Basis for DBP Engagement of DARC

Figure 5

Binding interfaces of the DBP-RII∶DARC heterotetramer.

(A) Global view of the DBP-RII∶DARC heterotetramer, showing (B) the DBP-RII homodimeric interface, (C) DARC monomer A interactions, and (D) DARC monomer B interactions. DARC monomer A is in purple, DARC monomer B is in blue, DBP-RII monomer 1 is in green and DBP-RII monomer 2 is in yellow. Residue numbers are labeled and DARC residue labels are underlined.

Figure 5