Identification of a Functional Type VI Secretion System in Campylobacter jejuni Conferring Capsule Polysaccharide Sensitive Cytotoxicity
Figure 2
Gene organization of the T6SS clusters in C. jejuni strain 108 and related species.
(A) The C. jejuni genes are designated according to the proposed nomenclature [5], [29] as ttsA-M; alternative gene names in V. cholerae are given in brackets for comparison. Functionally related group of genes are indicated in the same color. The lines and numbers below the colored genes indicate the PCR products and primers used for cloning and sequencing by primer walking. The same PCR primer sets were used to determine the gene organization in other Hcp-positive C. jejuni strains. (B) Comparison of the T6SS gene cluster organizations in C. jejuni strain 108, C. coli strain RM2228, H. hepaticus strain ATCC51449 and V. cholerae strain V52. Functionally related group of genes are indicated in the same color. (C) Diagram indicating the site of insertion of the C. jejuni 108 T6SS gene cluster relative to the CJIE3 element of C. jejuni RM1221.