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24 Hours in the Life of HIV-1 in a T Cell Line

Figure 3

Host gene expression and viral integration.

(A) Distribution of observed rates of integration: six gene groups (color coded) were defined based on the number of integrations per megabasepair (Mbp). Genes with no observed integration are depicted in grey. (B) Average level of expression of the six gene groups in Mock and HIV-infected cells during the 24-hour experiment. (C) Expected number of integration events in individual genes based on an empiric integration rate of 5.5 proviruses per haploid genome and on 40,430 observed unique integration sites (approx. 1% of all events).

Figure 3

doi: https://doi.org/10.1371/journal.ppat.1003161.g003