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Evolution of an Eurasian Avian-like Influenza Virus in Naïve and Vaccinated Pigs

Figure 2

The mutational spectra of intra-host EA-SIV populations are highly dynamic.

Median joining networks derived from representative individual pigs in the naïve (A) and vaccinated (B) studies. Each network was inferred by compiling sequences from multiple days. The number of sequences that constituted the consensus is indicated and circles are sized relative to their frequency in the data set. The identification number and the order of each pig the transmission chain is shown at the bottom of each panel. Colors indicate the day in which the sample was taken relative to the start of the study. Black dots along the branches indicate individual mutations relative to the sequence of the node from which they are derived. Cycles represent alternative potential evolutionary pathways.

Figure 2

doi: https://doi.org/10.1371/journal.ppat.1002730.g002