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A Novel Mouse Model of Schistosoma haematobium Egg-Induced Immunopathology

Figure 4

S. haematobium egg-injected bladders accumulate a mixed inflammatory infiltrate dominated by eosinophils and neutrophils.

Congruent with histologic evaluation, serial flow cytometric analyses of single cell suspensions made from egg-injected bladders demonstrate progressive accumulation of (A) eosinophils (SiglecF+CCR3+), (B) neutrophils (CD11b+Gr-1+), (C) B cells (B220+), and—to a lesser extent— (D) T cells (CD3+).

Figure 4

doi: https://doi.org/10.1371/journal.ppat.1002605.g004