Severe Acute Respiratory Syndrome Coronavirus Envelope Protein Regulates Cell Stress Response and Apoptosis
Figure 10
Activation of the IRE-1 pathway in rSARS-CoV-ΔE-infected cells.
Vero E6 cells were infected with rSARS-CoV-ΔE or rSARS-CoV at an moi of 2. Splicing of XBP-1 mRNA was analyzed at different times pi using oligonucleotides flanking the splicing region. Numbers below the gel represent the percentage of spliced/unspliced forms of XBP-1.