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Open Access
Peer-reviewed
Research Article
A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo
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Natalia T. Freund ,
* E-mail: nfreund@rockefeller.edu
Affiliation Laboratory of Molecular Immunology, The Rockefeller University, New York, New York, United States of America
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Joshua A. Horwitz,
Affiliation Laboratory of Molecular Immunology, The Rockefeller University, New York, New York, United States of America
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Lilian Nogueira,
Affiliation Laboratory of Molecular Immunology, The Rockefeller University, New York, New York, United States of America
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Stuart A. Sievers,
Affiliation Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California, United States of America
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Louise Scharf,
Affiliation Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California, United States of America
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Johannes F. Scheid,
Affiliation Laboratory of Molecular Immunology, The Rockefeller University, New York, New York, United States of America
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Anna Gazumyan,
Affiliation Laboratory of Molecular Immunology, The Rockefeller University, New York, New York, United States of America
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Cassie Liu,
Affiliation Laboratory of Molecular Immunology, The Rockefeller University, New York, New York, United States of America
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Klara Velinzon,
Affiliation Laboratory of Molecular Immunology, The Rockefeller University, New York, New York, United States of America
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Ariel Goldenthal,
Affiliation Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America
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Rogier W. Sanders,
Affiliation Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
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John P. Moore,
Affiliation Department of Microbiology and Immunology, Weill Medical College, Cornell University, New York, New York, United States of America
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Pamela J. Bjorkman,
Affiliation Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California, United States of America
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Michael S. Seaman,
Affiliation Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
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Bruce D. Walker,
Affiliations Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America, Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America
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Florian Klein,
Affiliations First Department of Internal Medicine, University Hospital of Cologne, Cologne, Germany, Center for Molecular Medicine Cologne (CMMC), University of Cologne, Germany
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Michel C. Nussenzweig
Affiliations Laboratory of Molecular Immunology, The Rockefeller University, New York, New York, United States of America, Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America
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A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo
- Natalia T. Freund,
- Joshua A. Horwitz,
- Lilian Nogueira,
- Stuart A. Sievers,
- Louise Scharf,
- Johannes F. Scheid,
- Anna Gazumyan,
- Cassie Liu,
- Klara Velinzon,
- Ariel Goldenthal
- Published: October 30, 2015
- https://doi.org/10.1371/journal.ppat.1005238