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Open Access
Peer-reviewed
Research Article
CD39 Expression Identifies Terminally Exhausted CD8+ T Cells
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Prakash K. Gupta ,
Contributed equally to this work with: Prakash K. Gupta, Jernej Godec, David Wolski
Affiliations Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom
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Jernej Godec ,
Contributed equally to this work with: Prakash K. Gupta, Jernej Godec, David Wolski
Affiliations Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Microbiology and Immunobiology and Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women’s Hospital, Boston, Massachusetts, United States of America
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David Wolski ,
Contributed equally to this work with: Prakash K. Gupta, Jernej Godec, David Wolski
Affiliation Gastrointestinal Unit, Massachusetts General Hospital and Harvard Medical School, Massachusetts, United States of America
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Emily Adland,
Affiliation Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom
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Kathleen Yates,
Affiliation Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America
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Kristen E. Pauken,
Affiliation Department of Microbiology and Institute for Immunology, University of Pennsylvania Perelman School Medicine, Philadelphia, Pennsylvania, United States of America
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Cormac Cosgrove,
Affiliation Ragon Institute of Massachusetts General Hospital, Harvard University and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
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Carola Ledderose,
Affiliation Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
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Wolfgang G. Junger,
Affiliation Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
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Simon C. Robson,
Affiliation Division of Gastroenterology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard University, Boston, Massachusetts, United States of America
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E. John Wherry,
Affiliation Department of Microbiology and Institute for Immunology, University of Pennsylvania Perelman School Medicine, Philadelphia, Pennsylvania, United States of America
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Galit Alter,
Affiliation Ragon Institute of Massachusetts General Hospital, Harvard University and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
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Philip J. R. Goulder,
Affiliation Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom
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Paul Klenerman,
Affiliation Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, United Kingdom
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Arlene H. Sharpe,
Affiliations Department of Microbiology and Immunobiology and Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women’s Hospital, Boston, Massachusetts, United States of America, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America
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Georg M. Lauer,
Affiliation Gastrointestinal Unit, Massachusetts General Hospital and Harvard Medical School, Massachusetts, United States of America
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W. Nicholas Haining
* E-mail: Nicholas_Haining@dfci.harvard.edu
Affiliations Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Division of Hematology/Oncology, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
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CD39 Expression Identifies Terminally Exhausted CD8+ T Cells
- Prakash K. Gupta,
- Jernej Godec,
- David Wolski,
- Emily Adland,
- Kathleen Yates,
- Kristen E. Pauken,
- Cormac Cosgrove,
- Carola Ledderose,
- Wolfgang G. Junger,
- Simon C. Robson
- Published: October 20, 2015
- https://doi.org/10.1371/journal.ppat.1005177