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Open Access
Peer-reviewed
Research Article
Comprehensive Antigenic Map of a Cleaved Soluble HIV-1 Envelope Trimer
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Ronald Derking,
Affiliation Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
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Gabriel Ozorowski,
Affiliations Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America, Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute, La Jolla, California, United States of America
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Kwinten Sliepen,
Affiliation Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
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Anila Yasmeen,
Affiliation Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York, United States of America
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Albert Cupo,
Affiliation Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York, United States of America
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Jonathan L. Torres,
Affiliations Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America, Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute, La Jolla, California, United States of America
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Jean-Philippe Julien,
Affiliations Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America, Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute, La Jolla, California, United States of America, Program in Molecular Structure and Function, The Hospital for Sick Children Research Institute and Departments of Biochemistry and Immunology, University of Toronto, Toronto, Ontario, Canada
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Jeong Hyun Lee,
Affiliations Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America, Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute, La Jolla, California, United States of America
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Thijs van Montfort,
Affiliation Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
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Steven W. de Taeye,
Affiliation Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
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Mark Connors,
Affiliation HIV-Specific Immunity Section, Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
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Dennis R. Burton,
Affiliations Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute, La Jolla, California, United States of America, Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America, Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, United States of America
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Ian A. Wilson,
Affiliations Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America, Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute, La Jolla, California, United States of America, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America
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Per-Johan Klasse,
Affiliation Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York, United States of America
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Andrew B. Ward,
Affiliations Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America, Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute, La Jolla, California, United States of America
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John P. Moore,
Affiliation Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York, United States of America
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Rogier W. Sanders
* E-mail: rws2002@med.cornell.edu
Affiliations Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York, United States of America
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Comprehensive Antigenic Map of a Cleaved Soluble HIV-1 Envelope Trimer
- Ronald Derking,
- Gabriel Ozorowski,
- Kwinten Sliepen,
- Anila Yasmeen,
- Albert Cupo,
- Jonathan L. Torres,
- Jean-Philippe Julien,
- Jeong Hyun Lee,
- Thijs van Montfort,
- Steven W. de Taeye
- Published: March 25, 2015
- https://doi.org/10.1371/journal.ppat.1004767