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Open Access
Peer-reviewed
Research Article
DENV Inhibits Type I IFN Production in Infected Cells by Cleaving Human STING
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Sebastian Aguirre,
Affiliation Department of Microbiology and the Global Health and Emerging Pathogens Institute, Mount Sinai School of Medicine, New York City, New York, United States of America
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Ana M. Maestre,
Affiliation Department of Microbiology and the Global Health and Emerging Pathogens Institute, Mount Sinai School of Medicine, New York City, New York, United States of America
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Sarah Pagni,
Affiliations Department of Microbiology and the Global Health and Emerging Pathogens Institute, Mount Sinai School of Medicine, New York City, New York, United States of America, Mount Sinai Graduate School of Biological Sciences, Mount Sinai School of Medicine, New York City, New York, United States of America
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Jenish R. Patel,
Affiliations Department of Microbiology and the Global Health and Emerging Pathogens Institute, Mount Sinai School of Medicine, New York City, New York, United States of America, Mount Sinai Graduate School of Biological Sciences, Mount Sinai School of Medicine, New York City, New York, United States of America
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Timothy Savage,
Affiliation Department of Microbiology and the Global Health and Emerging Pathogens Institute, Mount Sinai School of Medicine, New York City, New York, United States of America
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Delia Gutman,
Affiliation Department of Cell Biology, University of Miami School of Medicine, Miami, Florida, United States of America
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Kevin Maringer,
Affiliations Department of Microbiology and the Global Health and Emerging Pathogens Institute, Mount Sinai School of Medicine, New York City, New York, United States of America, School of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom
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Dabeiba Bernal-Rubio,
Affiliation Department of Microbiology and the Global Health and Emerging Pathogens Institute, Mount Sinai School of Medicine, New York City, New York, United States of America
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Reed S. Shabman,
Affiliation Department of Microbiology and the Global Health and Emerging Pathogens Institute, Mount Sinai School of Medicine, New York City, New York, United States of America
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Viviana Simon,
Affiliations Department of Microbiology and the Global Health and Emerging Pathogens Institute, Mount Sinai School of Medicine, New York City, New York, United States of America, Department of Medicine, Division of Infectious Diseases, Mount Sinai School of Medicine, New York City, New York, United States of America
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Juan R. Rodriguez-Madoz,
Affiliations Department of Microbiology and the Global Health and Emerging Pathogens Institute, Mount Sinai School of Medicine, New York City, New York, United States of America, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain
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Lubbertus C. F. Mulder,
Affiliations Department of Microbiology and the Global Health and Emerging Pathogens Institute, Mount Sinai School of Medicine, New York City, New York, United States of America, Department of Medicine, Division of Infectious Diseases, Mount Sinai School of Medicine, New York City, New York, United States of America
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Glen N. Barber,
Affiliation Department of Cell Biology, University of Miami School of Medicine, Miami, Florida, United States of America
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Ana Fernandez-Sesma
* E-mail: ana.sesma@mssm.edu
Affiliations Department of Microbiology and the Global Health and Emerging Pathogens Institute, Mount Sinai School of Medicine, New York City, New York, United States of America, Mount Sinai Graduate School of Biological Sciences, Mount Sinai School of Medicine, New York City, New York, United States of America, Department of Medicine, Division of Infectious Diseases, Mount Sinai School of Medicine, New York City, New York, United States of America
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DENV Inhibits Type I IFN Production in Infected Cells by Cleaving Human STING
- Sebastian Aguirre,
- Ana M. Maestre,
- Sarah Pagni,
- Jenish R. Patel,
- Timothy Savage,
- Delia Gutman,
- Kevin Maringer,
- Dabeiba Bernal-Rubio,
- Reed S. Shabman,
- Viviana Simon
- Published: October 4, 2012
- https://doi.org/10.1371/journal.ppat.1002934