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Open Access
Peer-reviewed
Research Article
Small Molecule Inhibitors of Staphylococcus aureus RnpA Alter Cellular mRNA Turnover, Exhibit Antimicrobial Activity, and Attenuate Pathogenesis
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Patrick D. Olson,
Affiliation Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, United States of America
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Lisa J. Kuechenmeister,
Affiliation Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, United States of America
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Kelsi L. Anderson,
Affiliation Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, United States of America
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Sonja Daily,
Affiliation Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America
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Karen E. Beenken,
Affiliation Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America
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Christelle M. Roux,
Affiliation Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, United States of America
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Michelle L. Reniere,
Affiliation Department of Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
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Tami L. Lewis,
Affiliation Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, United States of America
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William J. Weiss,
Affiliation Department of Molecular Biology and Immunology, University of North Texas Health Science Center, Fort Worth, Texas, United States of America
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Mark Pulse,
Affiliation Department of Molecular Biology and Immunology, University of North Texas Health Science Center, Fort Worth, Texas, United States of America
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Phung Nguyen,
Affiliation Department of Molecular Biology and Immunology, University of North Texas Health Science Center, Fort Worth, Texas, United States of America
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Jerry W. Simecka,
Affiliation Department of Molecular Biology and Immunology, University of North Texas Health Science Center, Fort Worth, Texas, United States of America
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John M. Morrison,
Affiliation Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, United States of America
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Khalid Sayood,
Affiliation Department of Electrical Engineering, University of Nebraska, Lincoln, Nebraska, United States of America
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Oluwatoyin A. Asojo,
Affiliation Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, United States of America
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Mark S. Smeltzer,
Affiliation Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America
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Eric P. Skaar,
Affiliation Department of Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
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Paul M. Dunman
* E-mail: Paul_Dunman@urmc.rochester.edu
Affiliations Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, United States of America, Department of Microbiology and Immunology, University of Rochester, Rochester, New York, United States of America
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Small Molecule Inhibitors of Staphylococcus aureus RnpA Alter Cellular mRNA Turnover, Exhibit Antimicrobial Activity, and Attenuate Pathogenesis
- Patrick D. Olson,
- Lisa J. Kuechenmeister,
- Kelsi L. Anderson,
- Sonja Daily,
- Karen E. Beenken,
- Christelle M. Roux,
- Michelle L. Reniere,
- Tami L. Lewis,
- William J. Weiss,
- Mark Pulse
- Published: February 10, 2011
- https://doi.org/10.1371/journal.ppat.1001287