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Posted by BenHowden on 24 Nov 2011 at 00:23 GMT

study highlights the dramatic impacts of single mutations that arise during persistent S. aureus infections and demonstrates the role played by walKR to increase drug resistance, control metabolism and alter the virulence potential of this pathogen
http://plospathogens.org/article/info:doi/10.1371/journal.ppat.1002359#article1.front1.article-meta1.abstract1.p1

Please see the following link for discussion of this project and the role of whole genome sequencing in uncovering the resistance mechanisms:
http://www.youtube.com/watch?v=PqTpx8Rc2OY

No competing interests declared.