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we used MS to improve resolution of MetSO data

Posted by johnmarkcarter on 01 Feb 2011 at 03:59 GMT

Using mass spectrometry to identify and quantitate sulfoxidation of methionine we found that sulfoxidation of Met213 is probably *not* involved in prion structure conversion. This work was published in Biochemistry: Silva, et al 2010, Biochemistry, 49:1854. It remains possible that Met206 is important.

No competing interests declared.