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Chromatin remodelling targeting by plant pathogens

Posted by mrr5 on 27 Oct 2010 at 11:56 GMT

The authors suggest that Agrobacterium is the only known example of a plant pathogen that modifies host histones, but the HC Toxin of the maize pathogen Cochliobolus carbonum CCR1 was identified some time ago as a potent inhibitor of histone deacetylases (Plant Cell 7; 1941-1950 (1995)). HC toxin is a key determinant of virulence in this pathogen, though the link between virulence and host histone acetylation is unknown.

No competing interests declared.