Reader Comments

Post a new comment on this article

structural basis of human CSF-1 inactivation by BARF1

Posted by savvas on 18 Feb 2013 at 20:30 GMT

The structural and mechanistic basis of inactivation of human CSF-1 by the secreted EBV protein BARF1 has recently been addressed in:

Elegheert J. et al.
Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1.
Nature Structural & Molecular Biology 19:938-47 (2012)

and,

Shim A. et al.
Multipronged attenuation of macrophage-colony stimulating factor signaling by Epstein-Barr virus BARF1.
Proc Natl Acad Sci U S A. 109:12962-7 (2012).

No competing interests declared.