About the Authors

Nicole A. Doria-Rose

Affiliation Vaccine Research Center, National Institutes of Health, Bethesda, MD, United States of America

Han R. Altae-Tran

Affiliation Vaccine Research Center, National Institutes of Health, Bethesda, MD, United States of America

Ryan S. Roark

Affiliation Vaccine Research Center, National Institutes of Health, Bethesda, MD, United States of America

Stephen D. Schmidt

Affiliation Vaccine Research Center, National Institutes of Health, Bethesda, MD, United States of America

Matthew S. Sutton

Affiliation Vaccine Research Center, National Institutes of Health, Bethesda, MD, United States of America

Mark K. Louder

Affiliation Vaccine Research Center, National Institutes of Health, Bethesda, MD, United States of America

Gwo-Yu Chuang

Affiliation Vaccine Research Center, National Institutes of Health, Bethesda, MD, United States of America

Robert T. Bailer

Affiliation Vaccine Research Center, National Institutes of Health, Bethesda, MD, United States of America

Valerie Cortez

Affiliations Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States of America, Program in Molecular and Cellular Biology, University of Washington, Seattle, WA, United States of America

Rui Kong

Affiliation Vaccine Research Center, National Institutes of Health, Bethesda, MD, United States of America

Krisha McKee

Affiliation Vaccine Research Center, National Institutes of Health, Bethesda, MD, United States of America

Sijy O’Dell

Affiliation Vaccine Research Center, National Institutes of Health, Bethesda, MD, United States of America

Felicia Wang

Affiliation Vanderbilt Vaccine Center, Vanderbilt University, Nashville, TN, United States of America

Salim S. Abdool Karim

Affiliations Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, South Africa, Department of Epidemiology, Columbia University, New York, NY, United States of America

James M. Binley

Affiliation San Diego Biomedical Research Institute, San Diego, CA, United States of America

Mark Connors

Affiliation HIV-Specific Immunity Section, National Institutes of Health, Bethesda, MD, United States of America

Barton F. Haynes

Affiliations Duke University Human Vaccine Institute, Durham, NC, United States of America, Departments of Medicine and Immunology, Duke University School of Medicine, Durham, NC, United States of America, Center for HIV/AIDS Vaccine Immunology-Immunogen Discovery at Duke University, Durham, NC, United States of America

Malcolm A. Martin

Affiliation Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America

David C. Montefiori

Affiliations Duke University Human Vaccine Institute, Durham, NC, United States of America, Department of Surgery, Duke University School of Medicine, Durham, NC, United States of America

Lynn Morris

Affiliations Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, South Africa, University of the Witwatersrand, Johannesburg, South Africa, Center for HIV and STIs, National Institute for Communicable Diseases, Johannesburg, South Africa

Julie Overbaugh

Affiliation Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States of America

Peter D. Kwong

Affiliation Vaccine Research Center, National Institutes of Health, Bethesda, MD, United States of America

John R. Mascola

Affiliation Vaccine Research Center, National Institutes of Health, Bethesda, MD, United States of America

Ivelin S. Georgiev

ivelin.georgiev@vanderbilt.edu

Affiliations Vaccine Research Center, National Institutes of Health, Bethesda, MD, United States of America, Vanderbilt Vaccine Center, Vanderbilt University, Nashville, TN, United States of America, Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States of America, Department of Electrical Engineering and Computer Science, Vanderbilt University, Nashville, TN, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ISG NADR HRAT. Performed the experiments: NADR HRAT RSR SDS MSS RTB GYC MKL KM SO FW ISG. Analyzed the data: NADR HRAT RSR SDS MSS RTB GYC MKL KM SO FW PDK JRM ISG. Contributed reagents/materials/analysis tools: VC RK MKL SSAK MC BFH MAM DCM LM JO. Wrote the paper: NADR HRAT JRM LM JMB ISG.