About the Authors

Mary F. Kearney

kearneym@ncifcrf.gov

Affiliation HIV-1 Drug Resistance Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America

Jonathan Spindler

Affiliation HIV-1 Drug Resistance Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America

Wei Shao

Affiliation Advanced Biomedical Computing Center, SAIC, Frederick, Maryland, United States of America

Sloane Yu

Affiliation HIV-1 Drug Resistance Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America

Elizabeth M. Anderson

Affiliation HIV-1 Drug Resistance Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America

Angeline O'Shea

Affiliation Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, NIH Bethesda, Maryland, United States of America

Catherine Rehm

Affiliation Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, NIH Bethesda, Maryland, United States of America

Carry Poethke

Affiliation HIV-1 Drug Resistance Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America

Nicholas Kovacs

Affiliation HIV-1 Drug Resistance Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America

John W. Mellors

Affiliation Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

John M. Coffin

Affiliation Department of Molecular Biology and Microbiology, Tufts University, Boston, Massachusetts, United States of America

Frank Maldarelli

Affiliation HIV-1 Drug Resistance Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, United States of America

Competing Interests

John Mellors is a consultant for Gilead Sciences and owns share options in RFS Pharmaceuticals. This does not alter our adherence to all PLoS Pathogens policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MFK JWM JMC FM. Performed the experiments: MFK JS SY. Analyzed the data: WS EMA NK. Contributed reagents/materials/analysis tools: MFK FM AOS CR CP. Wrote the paper: MFK JWM JMC FM.