About the Authors

Lena Serghides, Kevin C. Kain
Toronto General Research Institute, University Health Network, Toronto, Ontario, Canada

Lena Serghides, Chloe R. McDonald, Ziyue Lu, Kevin C. Kain
SA Rotman Laboratories, Sandra Rotman Centre for Global Health, University Health Network, Toronto, Ontario, Canada

Lena Serghides
Women's College Research Institute, Women's College Hospital, Toronto, Ontario, Canada

Chloe R. McDonald, Ziyue Lu, Cheryl Cui, Kevin C. Kain
Tropical Disease Unit, Division of Infectious Diseases, Department of Medicine, University of Toronto, Toronto, Ontario, Canada

Miriam Friedel, John G. Sled
Mouse Imaging Centre, Hospital for Sick Children, Toronto, Ontario, Canada

Keith T. Ho, Howard T. J. Mount
Department of Physiology, University of Toronto, Toronto, Ontario, Canada

Howard T. J. Mount
Department of Psychiatry, Department of Medicine, University of Toronto, Toronto, Ontario, Canada

John G. Sled
Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada

Corresponding Author

lena.serghides@utoronto.ca

Competing Interests

I have read the journal's policy and have the following conflicts: The University Health Network holds intellectual property pertaining to the use of PPARγ agonists for the treatment of severe malaria. The authors have no other financial interests related to this work. This does not alter our adherence to all PLOS Pathogens policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: LS CRM KCK. Performed the experiments: LS CRM ZL CC MF. Analyzed the data: LS CRM ZL MF JGS KCK. Contributed reagents/materials/analysis tools: JGS KTH HTJM. Wrote the paper: LS KCK.