About the Authors

Jean-Philippe Julien

Affiliations Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America, IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America, CHAVI-ID, The Scripps Research Institute, La Jolla, California, United States of America

Devin Sok

Affiliations IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America, CHAVI-ID, The Scripps Research Institute, La Jolla, California, United States of America, Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America

Reza Khayat

Affiliations Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America, IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America, CHAVI-ID, The Scripps Research Institute, La Jolla, California, United States of America

Jeong Hyun Lee

Affiliations Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America, IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America, CHAVI-ID, The Scripps Research Institute, La Jolla, California, United States of America

Katie J. Doores

Affiliations IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America, CHAVI-ID, The Scripps Research Institute, La Jolla, California, United States of America, Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America

Laura M. Walker

Affiliations IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America, CHAVI-ID, The Scripps Research Institute, La Jolla, California, United States of America, Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America

Alejandra Ramos

Affiliation IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America

Devan C. Diwanji

Affiliations Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America, IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America, CHAVI-ID, The Scripps Research Institute, La Jolla, California, United States of America

Robert Pejchal

Affiliations Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America, IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America, CHAVI-ID, The Scripps Research Institute, La Jolla, California, United States of America

Albert Cupo

Affiliation Weill Medical College of Cornell University, New York, New York, United States of America

Umesh Katpally

Affiliation Weill Medical College of Cornell University, New York, New York, United States of America

Rafael S. Depetris

Affiliation Weill Medical College of Cornell University, New York, New York, United States of America

Robyn L. Stanfield

Affiliations Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America, IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America, CHAVI-ID, The Scripps Research Institute, La Jolla, California, United States of America

Ryan McBride

Affiliation Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, United States of America

Andre J. Marozsan

Affiliation Weill Medical College of Cornell University, New York, New York, United States of America

James C. Paulson

Affiliations Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America, Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, United States of America

Rogier W. Sanders

Affiliations Weill Medical College of Cornell University, New York, New York, United States of America, Department of Medical Microbiology, Academic Medical Center, Amsterdam, Netherlands

John P. Moore

Affiliation Weill Medical College of Cornell University, New York, New York, United States of America

Dennis R. Burton

Affiliations IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America, CHAVI-ID, The Scripps Research Institute, La Jolla, California, United States of America, Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America, Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, United States of America

Pascal Poignard

Affiliations IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America, Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America

Andrew B. Ward

abward@scripps.edu (ABW); wilson@scripps.edu (IAW)

Affiliations Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America, IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America, CHAVI-ID, The Scripps Research Institute, La Jolla, California, United States of America

Ian A. Wilson

abward@scripps.edu (ABW); wilson@scripps.edu (IAW)

Affiliations Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America, IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America, CHAVI-ID, The Scripps Research Institute, La Jolla, California, United States of America, Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JPJ DS RK JHL KJD LMW RP AC UK RSD RLS RM AJM JCP RWS JPM DRB PP ABW IAW. Performed the experiments: JPJ DS RK JHL KJD LMW AR RP AC UK RSD RLS RM AJM. Analyzed the data: JPJ DS RK JHL KJD LMW AR DCD RP AC UK RSD RLS RM AJM JCP RWS JPM DRB PP ABW IAW. Wrote the paper: JPJ DS RK JHL KJD JCP RWS JPM DRB PP ABW IAW.