About the Authors

Julien R. C. Bergeron

Contributed equally to this work with: Julien R. C. Bergeron, Liam J. Worrall, Nikolaos G. Sgourakis

Affiliation Department of Biochemistry and Molecular Biology, and Centre for Blood Research, University of British Columbia, Vancouver, British Columbia, Canada

Liam J. Worrall

Contributed equally to this work with: Julien R. C. Bergeron, Liam J. Worrall, Nikolaos G. Sgourakis

Affiliation Department of Biochemistry and Molecular Biology, and Centre for Blood Research, University of British Columbia, Vancouver, British Columbia, Canada

Nikolaos G. Sgourakis

Contributed equally to this work with: Julien R. C. Bergeron, Liam J. Worrall, Nikolaos G. Sgourakis

Address Current address: Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.

Affiliation Department of Biochemistry, University of Washington, Seattle, Washington, United States of America

Frank DiMaio

Affiliation Department of Biochemistry, University of Washington, Seattle, Washington, United States of America

Richard A. Pfuetzner

Affiliation Department of Microbiology, University of Washington, Seattle, Washington, United States of America

Heather B. Felise

Address Current address: Department of Biological Sciences, Moravian College, Bethlehem, Pennsylvania, United States of America.

Affiliation Department of Microbiology, University of Washington, Seattle, Washington, United States of America

Marija Vuckovic

Affiliation Department of Biochemistry and Molecular Biology, and Centre for Blood Research, University of British Columbia, Vancouver, British Columbia, Canada

Angel C. Yu

Affiliation Department of Biochemistry and Molecular Biology, and Centre for Blood Research, University of British Columbia, Vancouver, British Columbia, Canada

Samuel I. Miller

Affiliations Department of Microbiology, University of Washington, Seattle, Washington, United States of America, Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America, Department of Medicine, University of Washington, Seattle, Washington, United States of America

David Baker

dabaker@uw.edu (DB); ncjs@mail.ubc.ca (NCJS)

Affiliations Department of Biochemistry, University of Washington, Seattle, Washington, United States of America, Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America, Howard Hughes Medical Institute, University of Washington, Seattle, Washington, United States of America

Natalie C. J. Strynadka

dabaker@uw.edu (DB); ncjs@mail.ubc.ca (NCJS)

Affiliation Department of Biochemistry and Molecular Biology, and Centre for Blood Research, University of British Columbia, Vancouver, British Columbia, Canada

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JRCB LJW NGS DB NCJS. Performed the experiments: JRCB LJW NGS FDM RAP HBF MV ACY. Analyzed the data: JRCB LJW NGS DB NCJS. Contributed reagents/materials/analysis tools: SIM. Wrote the paper: JRCB LJW NGS DB NCJS.