About the Authors

Dustin E. Bosch

Contributed equally to this work with: Dustin E. Bosch, Adam J. Kimple

Affiliation Department of Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

Adam J. Kimple

Contributed equally to this work with: Dustin E. Bosch, Adam J. Kimple

Affiliation Department of Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

Robin E. Muller

Affiliation Department of Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

Patrick M. Giguère

Affiliation Department of Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

Mischa Machius

Affiliation Department of Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

Francis S. Willard

Address Current address: Lilly Research Laboratories, Eli Lilly and Co., Indianapolis, Indiana, United States of America.

Affiliation Department of Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

Brenda R. S. Temple

Affiliations Department of Biochemistry & Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, R. L. Juliano Structural Bioinformatics Core, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

David P. Siderovski

dpsiderovski@hsc.wvu.edu

Affiliation Department of Physiology & Pharmacology, West Virginia University School of Medicine, Robert C. Byrd Health Sciences Center, Morgantown, West Virginia, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DEB AJK FSW DPS. Performed the experiments: DEB AJK REM PMG MM BRST. Analyzed the data: DEB AJK REM MM BRST DPS. Contributed reagents/materials/analysis tools: MM. Wrote the paper: DEB AJK DPS.