About the Authors

Eva Heinz

Affiliation Institute for Cell and Molecular Biosciences, The Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom

Tom A. Williams

Affiliation Institute for Cell and Molecular Biosciences, The Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom

Sirintra Nakjang

Affiliation Institute for Cell and Molecular Biosciences, The Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom

Christophe J. Noël

Affiliation Institute for Cell and Molecular Biosciences, The Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom

Daniel C. Swan

Affiliation Institute for Cell and Molecular Biosciences, The Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom

Alina V. Goldberg

Affiliation Institute for Cell and Molecular Biosciences, The Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom

Simon R. Harris

Affiliation Institute for Cell and Molecular Biosciences, The Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom

Thomas Weinmaier

Affiliation Department of Computational Systems Biology, University of Vienna, Vienna, Austria

Stephanie Markert

Affiliation Institute of Pharmacy, Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany

Dörte Becher

Affiliation Institute of Microbiology, Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany

Jörg Bernhardt

Affiliation Institute of Microbiology, Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany

Tal Dagan

Affiliation Institute for Molecular Evolution, Heinrich Heine University Düsseldorf, Düsseldorf, Germany

Christian Hacker

Affiliation School of Medicine, University of St Andrews, St Andrews, Scotland

John M. Lucocq

Affiliation School of Medicine, University of St Andrews, St Andrews, Scotland

Thomas Schweder

Affiliation Institute of Pharmacy, Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany

Thomas Rattei

Affiliation Department of Computational Systems Biology, University of Vienna, Vienna, Austria

Neil Hall

Affiliation Department of Functional and Comparative Genomics, School of Biological Sciences, University of Liverpool, Liverpool, United Kingdom

Robert P. Hirt

robert.hirt@newcastle.ac.uk (RPH); Martin.Embley@ncl.ac.uk (TME)

Affiliation Institute for Cell and Molecular Biosciences, The Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom

T. Martin Embley

robert.hirt@newcastle.ac.uk (RPH); Martin.Embley@ncl.ac.uk (TME)

Affiliation Institute for Cell and Molecular Biosciences, The Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TME RPH EH TAW SN SM CH JML TS TR NH. Performed the experiments: EH CJN AVG SM DB CH NH. Analyzed the data: EH TAW SN DCS SRH TW SM JB TD CH JML TS TR RPH TME. Contributed reagents/materials/analysis tools: CJN AVG EH. Wrote the paper: EH TAW SN SM TD CH JML RPH TME.