About the Authors
- Debrah A. Fine
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Contributed equally to this work with: Debrah A. Fine, Orit Rozenblatt-Rosen
Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Program in Virology, Harvard University Graduate School of Arts and Sciences, Division of Medical Sciences, Boston, Massachusetts, United States of America, Genomic Analysis of Network Perturbations Center of Excellence in Genomic Science, Center for Cancer Systems Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America
- Orit Rozenblatt-Rosen
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Contributed equally to this work with: Debrah A. Fine, Orit Rozenblatt-Rosen
Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Genomic Analysis of Network Perturbations Center of Excellence in Genomic Science, Center for Cancer Systems Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America
- Megha Padi
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Affiliations Genomic Analysis of Network Perturbations Center of Excellence in Genomic Science, Center for Cancer Systems Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Center for Cancer Computational Biology, Department of Biostatistics and Computational Biology and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America
- Anna Korkhin
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Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Genomic Analysis of Network Perturbations Center of Excellence in Genomic Science, Center for Cancer Systems Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America
- Robert L. James
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Affiliations Genomic Analysis of Network Perturbations Center of Excellence in Genomic Science, Center for Cancer Systems Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Center for Cancer Systems Biology and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America
- Guillaume Adelmant
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Affiliations Genomic Analysis of Network Perturbations Center of Excellence in Genomic Science, Center for Cancer Systems Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Blais Proteomics Center and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America
- Rosa Yoon
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Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Program in Virology, Harvard University Graduate School of Arts and Sciences, Division of Medical Sciences, Boston, Massachusetts, United States of America
- Luxuan Guo
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Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
- Christian Berrios
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Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Program in Virology, Harvard University Graduate School of Arts and Sciences, Division of Medical Sciences, Boston, Massachusetts, United States of America
- Ying Zhang
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Affiliation Stowers Institute for Medical Research, Kansas City, Missouri, United States of America
- Michael A. Calderwood
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Affiliations Genomic Analysis of Network Perturbations Center of Excellence in Genomic Science, Center for Cancer Systems Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Center for Cancer Systems Biology and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America
- Soundarapandian Velmurgan
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Affiliation Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America
- Jingwei Cheng
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Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
- Jarrod A. Marto
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Affiliations Genomic Analysis of Network Perturbations Center of Excellence in Genomic Science, Center for Cancer Systems Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Blais Proteomics Center and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America
- David E. Hill
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Affiliations Genomic Analysis of Network Perturbations Center of Excellence in Genomic Science, Center for Cancer Systems Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Center for Cancer Systems Biology and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America
- Michael E. Cusick
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Affiliations Genomic Analysis of Network Perturbations Center of Excellence in Genomic Science, Center for Cancer Systems Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Center for Cancer Systems Biology and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America
- Marc Vidal
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Affiliations Genomic Analysis of Network Perturbations Center of Excellence in Genomic Science, Center for Cancer Systems Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Center for Cancer Systems Biology and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America
- Laurence Florens
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Affiliation Stowers Institute for Medical Research, Kansas City, Missouri, United States of America
- Michael P. Washburn
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Affiliations Stowers Institute for Medical Research, Kansas City, Missouri, United States of America, Department of Pathology and Laboratory Medicine, The University of Kansas Medical Center, Kansas City, Kansas, United States of America
- Larisa Litovchick
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Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Genomic Analysis of Network Perturbations Center of Excellence in Genomic Science, Center for Cancer Systems Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
- James A. DeCaprio
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* E-mail: james_decaprio@dfci.harvard.edu
Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Program in Virology, Harvard University Graduate School of Arts and Sciences, Division of Medical Sciences, Boston, Massachusetts, United States of America, Genomic Analysis of Network Perturbations Center of Excellence in Genomic Science, Center for Cancer Systems Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
Conceived and designed the experiments: DAF ORR MP GA RY JAM DEH MV MPW LL JAD. Performed the experiments: DAF ORR AK RLJ GA RY LG CB YZ SV LL. Analyzed the data: DAF ORR MP AK RLJ GA RY MAC JAM DEH MEC LF LL JAD. Contributed reagents/materials/analysis tools: LG CB SV JC. Wrote the paper: DAF ORR MP GA RY YZ MAC JAM MEC LF LL JAD.