About the Authors

Ami A. Patel

Affiliations Department of Veterinary Pathobiology, University of Missouri, Columbia, Missouri, United States of America, Laboratory for Infectious Disease Research, University of Missouri, Columbia, Missouri, United States of America

Hanni Lee-Lewis

Affiliations Department of Veterinary Pathobiology, University of Missouri, Columbia, Missouri, United States of America, Laboratory for Infectious Disease Research, University of Missouri, Columbia, Missouri, United States of America

Jennifer Hughes-Hanks

Contributed equally to this work with: Jennifer Hughes-Hanks, Craig A. Lewis

Affiliation Department of Veterinary Pathobiology, University of Missouri, Columbia, Missouri, United States of America

Craig A. Lewis

Contributed equally to this work with: Jennifer Hughes-Hanks, Craig A. Lewis

Affiliation Starling Enterprise, LLC, Columbia, Missouri, United States of America

Deborah M. Anderson

andersondeb@missouri.edu

Affiliations Department of Veterinary Pathobiology, University of Missouri, Columbia, Missouri, United States of America, Laboratory for Infectious Disease Research, University of Missouri, Columbia, Missouri, United States of America

Competing Interests

Starling Enterprises offers statistical analysis of biological data as well as consulting on study design and analysis. Dr. Lewis is the chief officer of this company and there are no associated commercial products. Dr. Lewis was provided with all raw data collected for survival, titer, cytokine and real time PCR experiments shown in the paper and he returned appropriate statistical analyses on these data. There was no competing financial interest with Starling Enterprise. This does not alter our adherence to all PLoS Pathogens policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: AAP DMA. Performed the experiments: AAP. Analyzed the data: AAP JHH HLL CAL DMA. Wrote the paper: AAP DMA.