About the Authors

Craig B. Wilen

Affiliation Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

Jianbin Wang

Affiliation Sangamo BioSciences, Richmond, California, United States of America

John C. Tilton

Address Current address: Center for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, Ohio, United States of America.

Affiliation Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

Jeffrey C. Miller

Affiliation Sangamo BioSciences, Richmond, California, United States of America

Kenneth A. Kim

Affiliation Sangamo BioSciences, Richmond, California, United States of America

Edward J. Rebar

Affiliation Sangamo BioSciences, Richmond, California, United States of America

Scott A. Sherrill-Mix

Affiliation Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

Sean C. Patro

Affiliation Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

Anthony J. Secreto

Affiliation Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

Andrea P. O. Jordan

Affiliation Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

Gary Lee

Affiliation Sangamo BioSciences, Richmond, California, United States of America

Joshua Kahn

Affiliation Sangamo BioSciences, Richmond, California, United States of America

Pyone P. Aye

Affiliation Divisions of Regenerative Medicine and Comparative Pathology, Tulane National Primate Research Center, Tulane University School of Medicine, Covington, Louisiana, United States of America

Bruce A. Bunnell

Affiliation Divisions of Regenerative Medicine and Comparative Pathology, Tulane National Primate Research Center, Tulane University School of Medicine, Covington, Louisiana, United States of America

Andrew A. Lackner

Affiliation Divisions of Regenerative Medicine and Comparative Pathology, Tulane National Primate Research Center, Tulane University School of Medicine, Covington, Louisiana, United States of America

James A. Hoxie

Affiliation Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

Gwenn A. Danet-Desnoyers

Affiliation Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

Frederic D. Bushman

Affiliation Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

James L. Riley

Affiliation Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

Philip D. Gregory

Affiliation Sangamo BioSciences, Richmond, California, United States of America

Carl H. June

Affiliation Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

Michael C. Holmes

Affiliation Sangamo BioSciences, Richmond, California, United States of America

Robert W. Doms

doms@mail.med.upenn.edu

Affiliation Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

Competing Interests

A number of the authors are employed by Sangamo Biosciences. The work was funded by NIH.

Author Contributions

Conceived and designed the experiments: CBW JW JCT EJR SCP JAH GADD JLR PDG CHJ MCH RWD. Performed the experiments: CBW JW KAK SCP AJS APOJ. Analyzed the data: CBW JW JCM SCP. Contributed reagents/materials/analysis tools: SASM GL JK PPA BAB AAL FDB. Wrote the paper: CBW RWD.