About the Authors

Elena Gustchina

Contributed equally to this work with: Elena Gustchina, Mi Li, John M. Louis

Affiliation Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Mi Li

Contributed equally to this work with: Elena Gustchina, Mi Li, John M. Louis

Affiliations Protein Structure Section, Macromolecular Crystallography Laboratory, National Cancer Institute, Frederick, Maryland, United States of America, Basic Research Program, SAIC-Frederick, Frederick, Maryland, United States of America

John M. Louis

Contributed equally to this work with: Elena Gustchina, Mi Li, John M. Louis

Affiliation Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

D. Eric Anderson

Affiliation Proteomics and Mass Spectrometry Facility, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

John Lloyd

Affiliation Proteomics and Mass Spectrometry Facility, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Christian Frisch

Affiliation AbD Serotec, MorphoSys AG, Martinsried, Germany

Carole A. Bewley

Affiliation Laboratory of Biorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Alla Gustchina

mariusc@mail.nih.gov (GMC); wlodawer@nih.gov (AW); gustchia@mail.nih.gov (AG)

Affiliation Protein Structure Section, Macromolecular Crystallography Laboratory, National Cancer Institute, Frederick, Maryland, United States of America

Alexander Wlodawer

mariusc@mail.nih.gov (GMC); wlodawer@nih.gov (AW); gustchia@mail.nih.gov (AG)

Affiliation Protein Structure Section, Macromolecular Crystallography Laboratory, National Cancer Institute, Frederick, Maryland, United States of America

G. Marius Clore

mariusc@mail.nih.gov (GMC); wlodawer@nih.gov (AW); gustchia@mail.nih.gov (AG)

Affiliation Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JML CAB AG AW GMC. Performed the experiments: EG ML JML DEA JL. Analyzed the data: EG ML JML DEA JL AG AW GMC. Contributed reagents/materials/analysis tools: CF. Wrote the paper: EG CAB AG AW GMC.