About the Authors

Carl J. Baldick

joe.baldick@bms.com

Affiliation Bristol-Myers Squibb, Research and Development, Wallingford, Connecticut, United States of America

Michael J. Wichroski

Affiliation Bristol-Myers Squibb, Research and Development, Wallingford, Connecticut, United States of America

Annapurna Pendri

Affiliation Bristol-Myers Squibb, Research and Development, Wallingford, Connecticut, United States of America

Ann W. Walsh

Affiliation Bristol-Myers Squibb, Research and Development, Wallingford, Connecticut, United States of America

Jie Fang

Affiliation Bristol-Myers Squibb, Research and Development, Wallingford, Connecticut, United States of America

Charles E. Mazzucco

Affiliation Bristol-Myers Squibb, Research and Development, Wallingford, Connecticut, United States of America

Kevin A. Pokornowski

Affiliation Bristol-Myers Squibb, Research and Development, Wallingford, Connecticut, United States of America

Ronald E. Rose

Affiliation Bristol-Myers Squibb, Research and Development, Wallingford, Connecticut, United States of America

Betsy J. Eggers

Affiliation Bristol-Myers Squibb, Research and Development, Wallingford, Connecticut, United States of America

Mayla Hsu

Current address: Population Council, Center for Biomedical Research, New York, New York, United States of America

Affiliation Bristol-Myers Squibb, Research and Development, Wallingford, Connecticut, United States of America

Weixu Zhai

Affiliation Bristol-Myers Squibb, Research and Development, Wallingford, Connecticut, United States of America

Guangzhi Zhai

Affiliation Bristol-Myers Squibb, Research and Development, Wallingford, Connecticut, United States of America

Samuel W. Gerritz

Affiliation Bristol-Myers Squibb, Research and Development, Wallingford, Connecticut, United States of America

Michael A. Poss

Affiliation Bristol-Myers Squibb, Research and Development, Wallingford, Connecticut, United States of America

Nicholas A. Meanwell

Affiliation Bristol-Myers Squibb, Research and Development, Wallingford, Connecticut, United States of America

Mark I. Cockett

Affiliation Bristol-Myers Squibb, Research and Development, Wallingford, Connecticut, United States of America

Daniel J. Tenney

Affiliation Bristol-Myers Squibb, Research and Development, Wallingford, Connecticut, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CJB MJW AP CEM RER MH SWG MAP NAM DJT. Performed the experiments: CJB MJW AP AWW JF CEM KAP RER BJE MH WZ GZ. Analyzed the data: CJB MJW AP AWW JF CEM KAP RER BJE MH WZ GZ MIC. Contributed reagents/materials/analysis tools: CJB MJW AP AWW JF CEM KAP RER MH WZ. Wrote the paper: CJB DJT.