About the Authors

Roy R. Chaudhuri

Contributed equally to this work with: Roy R. Chaudhuri, Sarah E. Peters

Affiliation Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

Sarah E. Peters

Contributed equally to this work with: Roy R. Chaudhuri, Sarah E. Peters

Affiliation Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

Stephen J. Pleasance

Affiliation Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

Helen Northen

Affiliation Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

Chrissie Willers

Affiliation Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

Gavin K. Paterson

Affiliation Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

Danielle B. Cone

Address Current address: Health Protection Agency, Clinical Microbiology and Public Health Laboratory, Addenbrooke's Hospital, Cambridge, United Kingdom

Affiliation Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

Andrew G. Allen

Address Current address: Pfizer Australia, Veterinary Medicine Research and Development, Parkville, Victoria, Australia

Affiliation Arrow Therapeutics Ltd., London, United Kingdom

Paul J. Owen

Address Current address: Cancer Research Technology Development Laboratory, Wolfson Institute for Biomedical Research, London, United Kingdom

Affiliation Arrow Therapeutics Ltd., London, United Kingdom

Gil Shalom

Address Current address: Division of Microbial Diseases, UCL Eastman Dental Institute, London, United Kingdom

Affiliation Arrow Therapeutics Ltd., London, United Kingdom

Dov J. Stekel

Affiliation Centre for Systems Biology, School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom

Ian G. Charles

These authors are joint last authors on this work.

Affiliation Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, United Kingdom

Duncan J. Maskell

djm47@cam.ac.uk

These authors are joint last authors on this work.

Affiliation Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

Competing Interests

DJM and IGC are named inventors on the patent “Transposon Mediated Differential Hybridisation”, International Patent Number WO2001/007651. DJM, IGC, AGA and PJO are named inventors on the patent “Transposon”, International Patent Number WO2003/074700.

Author Contributions

Conceived and designed the experiments: RRC SEP AGA PJO GS IGC DJM. Performed the experiments: SEP SJP HN CW GKP DBC AGA PJO GS. Analyzed the data: RRC. Wrote the paper: RRC SEP IGC DJM. Developed the microarray analysis methods: RRC. Developed the transposons: SEP AGA PJO IGC DJM. Performed the initial development of the TMDH method: SEP AGA PJO GS IGC DJM. Performed the mouse screens: SEP HN CW AGA. Performed the array experiments and verification of the locations of transposon insertions: SJP. Generated and tested the individual mutants: SEP HN CW GKP DBC. Contributed to development of microarray analysis methods: DJS. Invented the TMDH approach: IGC DJM.