About the Authors

Roy R. Chaudhuri, Sarah E. Peters, Stephen J. Pleasance, Helen Northen, Chrissie Willers, Gavin K. Paterson, Danielle B. Cone, Duncan J. Maskell
Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

Andrew G. Allen, Paul J. Owen, Gil Shalom
Arrow Therapeutics Ltd., London, United Kingdom

Dov J. Stekel
Centre for Systems Biology, School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom

Ian G. Charles
Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, United Kingdom

Corresponding Author

djm47@cam.ac.uk

Competing Interests

DJM and IGC are named inventors on the patent “Transposon Mediated Differential Hybridisation”, International Patent Number WO2001/007651. DJM, IGC, AGA and PJO are named inventors on the patent “Transposon”, International Patent Number WO2003/074700.

Author Contributions

Conceived and designed the experiments: RRC SEP AGA PJO GS IGC DJM. Performed the experiments: SEP SJP HN CW GKP DBC AGA PJO GS. Analyzed the data: RRC. Wrote the paper: RRC SEP IGC DJM. Developed the microarray analysis methods: RRC. Developed the transposons: SEP AGA PJO IGC DJM. Performed the initial development of the TMDH method: SEP AGA PJO GS IGC DJM. Performed the mouse screens: SEP HN CW AGA. Performed the array experiments and verification of the locations of transposon insertions: SJP. Generated and tested the individual mutants: SEP HN CW GKP DBC. Contributed to development of microarray analysis methods: DJS. Invented the TMDH approach: IGC DJM.