About the Authors

Mia D. Champion

Contributed equally to this work with: Mia D. Champion, Qiandong Zeng

champion@broad.mit.edu

Affiliation Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Qiandong Zeng

Contributed equally to this work with: Mia D. Champion, Qiandong Zeng

Affiliation Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Eli B. Nix

Affiliation Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada

Francis E. Nano

Affiliation Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada

Paul Keim

Affiliations Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, Arizona, United States of America, Pathogen Genomics Division, Translational Genomics Research Institute, Phoenix, Arizona, United States of America

Chinnappa D. Kodira

Affiliation Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Mark Borowsky

Affiliation Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Sarah Young

Affiliation Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Michael Koehrsen

Affiliation Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Reinhard Engels

Affiliation Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Matthew Pearson

Affiliation Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Clint Howarth

Affiliation Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Lisa Larson

Affiliation Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Jared White

Affiliation Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Lucia Alvarado

Affiliation Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Mats Forsman

Affiliation Department of CBRN Defense and Security, Swedish Defense Research Agency, Umeå, Sweden

Scott W. Bearden

Affiliation Centers for Disease Control and Prevention, Division of Vector-Borne Infectious Diseases, Fort Collins, Colorado, United States of America

Anders Sjöstedt

Affiliation Department of Clinical Bacteriology, Clinical Microbiology, Umeå University, Umeå, Sweden

Richard Titball

Affiliation University of Exeter, School of Biosciences, Exeter, United Kingdom

Stephen L. Michell

Affiliation University of Exeter, School of Biosciences, Exeter, United Kingdom

Bruce Birren

Affiliation Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

James Galagan

Affiliations Microbial Analysis Group, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Boston University Department of Biomedical Engineering and the Boston University Medical School, Boston, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MDC QZ FEN PK MB MF SWB AS RWT BB JEG. Performed the experiments: MDC QZ EBN SY. Analyzed the data: MDC QZ EBN FEN PK CDK SY BB JEG. Contributed reagents/materials/analysis tools: MDC QZ EBN FEN PK MB MK RE MP CH LL JW LA MF SWB AS. Wrote the paper: MDC SLM. Contributed select draft sections of the paper in the early editing stages: QZ. Edited paper: FEN PK MF BB. Significant scientific advice and editing of the manuscript: RT. Editorial comments on the paper: SLM. Directed the Project and provided leadership: BB. Senior Author and provided editorial input: JG.