About the Authors

Darly J Manayani

Affiliation Department of Molecular Biology, The Scripps Research Institute, La Jolla, California , United States of America

Diane Thomas

Affiliation Department of Cell Biology, The Scripps Research Institute, La Jolla, California , United States of America

Kelly A Dryden

Affiliation Department of Cell Biology, The Scripps Research Institute, La Jolla, California , United States of America

Vijay Reddy

Affiliation Department of Molecular Biology, The Scripps Research Institute, La Jolla, California , United States of America

Marc E Siladi

Affiliation Department of Molecular Biology, The Scripps Research Institute, La Jolla, California , United States of America

John M Marlett

Affiliation The Salk Institute for Biological Studies, La Jolla, California, United States of America

G. Jonah A Rainey

Affiliation The Salk Institute for Biological Studies, La Jolla, California, United States of America

Michael E Pique

Affiliation Department of Molecular Biology, The Scripps Research Institute, La Jolla, California , United States of America

Heather M Scobie

Affiliation The Salk Institute for Biological Studies, La Jolla, California, United States of America

Mark Yeager

Affiliations Department of Molecular Biology, The Scripps Research Institute, La Jolla, California , United States of America , Department of Cell Biology, The Scripps Research Institute, La Jolla, California , United States of America , Division of Cardiovascular Diseases, Scripps Clinic, La Jolla, California, United States of America

John A. T Young

Affiliation The Salk Institute for Biological Studies, La Jolla, California, United States of America

Marianne Manchester

Affiliation Department of Cell Biology, The Scripps Research Institute, La Jolla, California , United States of America

Anette Schneemann

To whom correspondence should be addressed. E-mail: aschneem@scripps.edu

Affiliation Department of Molecular Biology, The Scripps Research Institute, La Jolla, California , United States of America

Competing Interests

The JATY declares competing financial interests. He is a scientific founder of the company PharmAthene Inc.

Author Contributions

DJM, MY, JATY, MM, and AS conceived and designed the experiments. DJM, DT, KAD, VR, MES, JMM, and GJAR performed the experiments. DJM, DT, KAD, VR, MES, JMM, MY, JATY, MM, and AS analyzed the data. MEP and HMS contributed reagents and analysis tools. DJM, MY, JATY, MM, and AS wrote the paper.