Apoptotic Killing of HIV-1–Infected Macrophages Is Subverted by the Viral Envelope Glycoprotein

Open Access

Peer-reviewed

Research Article

Simon Swingler,

Affiliation Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Angela M Mann,

Affiliation Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Jin Zhou,

Affiliation Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Catherine Swingler,

Affiliation Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Mario Stevenson

*To whom correspondence should be addressed. E-mail: Mario.stevenson@umassmed.edu

Affiliation Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯

About the Authors

Simon Swingler

Affiliation Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

Angela M Mann

Affiliation Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

Jin Zhou

Affiliation Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

Catherine Swingler

Affiliation Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

Mario Stevenson

*To whom correspondence should be addressed. E-mail: Mario.stevenson@umassmed.edu

Affiliation Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

The authors have declared that no competing interests exist.

SS and MS conceived and designed the experiments. SS, AMM, JZ, and CS performed the experiments. SS and MS analyzed the data and wrote the paper.

Macrophages
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Apoptosis
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HIV-1
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T cells
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Flow cytometry
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Enzyme-linked immunoassays
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Viral envelope
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Cytokines
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