Two Plasmodium Rhomboid Proteases Preferentially Cleave Different Adhesins Implicated in All Invasive Stages of Malaria

Rosanna P Baker; Ruvini Wijetilaka; Sinisa Urban

doi:10.1371/journal.ppat.0020113

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Peer-reviewed

Research Article

Two Plasmodium Rhomboid Proteases Preferentially Cleave Different Adhesins Implicated in All Invasive Stages of Malaria

Rosanna P Baker,

Affiliations Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America , Center of Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts, United States of America
⨯
Ruvini Wijetilaka,

Affiliation Center of Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts, United States of America
⨯
Sinisa Urban

*To whom correspondence should be addressed. E-mail: surban@jhmi.edu

Affiliations Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America , Center of Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts, United States of America
⨯

Two Plasmodium Rhomboid Proteases Preferentially Cleave Different Adhesins Implicated in All Invasive Stages of Malaria

Rosanna P Baker,
Ruvini Wijetilaka,
Sinisa Urban

Published: October 13, 2006
https://doi.org/10.1371/journal.ppat.0020113

About the Authors

Rosanna P Baker

Affiliations Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America , Center of Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts, United States of America

Ruvini Wijetilaka

Affiliation Center of Neurologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts, United States of America

Sinisa Urban

*To whom correspondence should be addressed. E-mail: surban@jhmi.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

SU conceived and designed the experiments. RPB, RW, and SU performed the experiments. RPB and SU analyzed the data. SU contributed reagents/materials/analysis tools. SU wrote the paper.

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Adhesins
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Plasmodium
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Proteases
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Merozoites
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Plasmodium falciparum
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Toxoplasma
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Transfection
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COS cells
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