About the Authors

Martina Kovarova

Contributed equally to this work with: Martina Kovarova, Olivia D. Council

kovarovm@med.unc.edu (MK); victor_garcia@med.unc.edu (JVG)

Affiliation Division of Infectious Diseases, Center for AIDS Research, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, North Carolina, United States of America

Olivia D. Council

Contributed equally to this work with: Martina Kovarova, Olivia D. Council

Affiliation Division of Infectious Diseases, Center for AIDS Research, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, North Carolina, United States of America

Abhijit A. Date

Affiliation Department of Pharmacy Practice, Creighton University School of Pharmacy and Health Professions, Omaha, Nebraska, United States of America

Julie M. Long

Affiliation Division of Infectious Diseases, Center for AIDS Research, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, North Carolina, United States of America

Tomonori Nochii

Affiliation Division of Infectious Diseases, Center for AIDS Research, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, North Carolina, United States of America

Michael Belshan

Affiliation Department of Pharmacy Practice, Creighton University School of Pharmacy and Health Professions, Omaha, Nebraska, United States of America

Annemarie Shibata

Affiliation Department of Pharmacy Practice, Creighton University School of Pharmacy and Health Professions, Omaha, Nebraska, United States of America

Heather Vincent

Affiliation Division of Infectious Diseases, Center for AIDS Research, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, North Carolina, United States of America

Caroline E. Baker

Affiliation Division of Infectious Diseases, Center for AIDS Research, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, North Carolina, United States of America

William O. Thayer

Affiliation Division of Infectious Diseases, Center for AIDS Research, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, North Carolina, United States of America

Guenter Kraus

Affiliation Janssen Research and Development, Beerse, Belgium

Sophie Lachaud-Durand

Affiliation Janssen Research and Development, Beerse, Belgium

Peter Williams

Affiliation Janssen Research and Development, Beerse, Belgium

Christopher J. Destache

Affiliation Department of Pharmacy Practice, Creighton University School of Pharmacy and Health Professions, Omaha, Nebraska, United States of America

J. Victor Garcia

kovarovm@med.unc.edu (MK); victor_garcia@med.unc.edu (JVG)

Affiliation Division of Infectious Diseases, Center for AIDS Research, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, North Carolina, United States of America

Competing Interests

I have read the journal's policy and the authors of this manuscript have the following competing interests: GK, SLD and PW are employed by Janssen Research and Development, LLC. This does not alter our adherence to all PLOS policies on sharing data and materials. Other authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CJD JVG. Performed the experiments: MK ODC AAD JML TN MB AS HV CEB WOT SLD. Analyzed the data: MK ODC AAD JML TN MB AS HV CEB WOT GK SLD. Contributed reagents/materials/analysis tools: GK SLD PW. Wrote the paper: MK PW CJD JVG.