About the Authors

Marnie L. Fusco

Affiliation Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America

Takao Hashiguchi

Affiliations Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America, Department of Virology, Faculty of Medicine, Kyushu University, Fukuoka, Japan

Robyn Cassan

Affiliation Emergent BioSolutions (formerly Cangene Corporation), Winnipeg, Manitoba, Canada

Julia E. Biggins

Affiliations Division of Virology, United States Army Research Institute for Infectious Disease, Ft. Detrick, Maryland, United States of America, Integrated Biotherapeutics, Inc., Gaithersburg, Maryland, United States of America

Charles D. Murin

Affiliations Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America, Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America

Kelly L. Warfield

Current address: Unither Virology, Silver Spring, Maryland, United States of America

Affiliation Integrated Biotherapeutics, Inc., Gaithersburg, Maryland, United States of America

Sheng Li

Affiliation Department of Medicine, University of California San Diego, La Jolla, California, United States of America

Frederick W. Holtsberg

Affiliation Integrated Biotherapeutics, Inc., Gaithersburg, Maryland, United States of America

Sergey Shulenin

Affiliation Integrated Biotherapeutics, Inc., Gaithersburg, Maryland, United States of America

Hong Vu

Affiliation Integrated Biotherapeutics, Inc., Gaithersburg, Maryland, United States of America

Gene G. Olinger

Affiliations Division of Virology, United States Army Research Institute for Infectious Disease, Ft. Detrick, Maryland, United States of America, Integrated Research Facility, NIAID, National Institutes of Health, Frederick, Maryland, United States of America

Do H. Kim

Affiliation Mapp Biopharmaceutical, Inc., San Diego, California, United States of America

Kevin J. Whaley

Affiliation Mapp Biopharmaceutical, Inc., San Diego, California, United States of America

Larry Zeitlin

Affiliation Mapp Biopharmaceutical, Inc., San Diego, California, United States of America

Andrew B. Ward

Affiliation Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America

Cory Nykiforuk

Affiliation Emergent BioSolutions (formerly Cangene Corporation), Winnipeg, Manitoba, Canada

M. Javad Aman

Affiliation Integrated Biotherapeutics, Inc., Gaithersburg, Maryland, United States of America

Jody Berry

Affiliation Emergent BioSolutions (formerly Cangene Corporation), Winnipeg, Manitoba, Canada

Erica Ollmann Saphire

erica@scripps.edu

Affiliations Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America, Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America

Competing Interests

I have read the journal's policy and the authors of this manuscript have the following competing interests: RC and CN are employed by Emergent BioSolutions, formerly Cangene Corp. JB was employed by Cangene Corp when this study was conceived and performed. MJA, SS, HV, FWH are employed by Integrated Biotherapeutics. KLW was employed by Integrated Biotherapeutics when this study was conceived and performed. KJW and LZ are employed by Mapp Biopharmaceutical. These and other authors have pending patent applications on several of the described antibodies. This does not alter our adherence to all PLOS Pathogens policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MLF TH EOS LZ JB MJA KLW GGO ABW CDM. Performed the experiments: MLF TH CDM JEB HV RC GGO SS FWH DHK SL. Analyzed the data: EOS MLF CDM ABW. Contributed reagents/materials/analysis tools: LZ MJA KLW EOS RC MLF TH CN KJW. Wrote the paper: MLF EOS.