About the Authors

Teagan Guarnaccia

Affiliations WHO Collaborating Centre for Reference and Research on Influenza, Victorian Infectious Diseases Reference Laboratory, Melbourne, Victoria, Australia, Monash University, School of Applied Sciences, Churchill, Victoria, Australia

Louise A. Carolan

Affiliation WHO Collaborating Centre for Reference and Research on Influenza, Victorian Infectious Diseases Reference Laboratory, Melbourne, Victoria, Australia

Sebastian Maurer-Stroh

Affiliations Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore, National Public Health Laboratory, Communicable Diseases Division Ministry of Health, Singapore, School of Biological Sciences (SBS), Nanyang Technological University (NTU), Singapore

Raphael T. C. Lee

Affiliation Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore

Emma Job

Affiliation The University of Melbourne, Department Microbiology & Immunology, Melbourne, Victoria, Australia

Patrick C. Reading

Affiliations WHO Collaborating Centre for Reference and Research on Influenza, Victorian Infectious Diseases Reference Laboratory, Melbourne, Victoria, Australia, The University of Melbourne, Department Microbiology & Immunology, Melbourne, Victoria, Australia

Stephen Petrie

Affiliation The University of Melbourne, Melbourne School of Population Health, Melbourne, Victoria, Australia

James M. McCaw

Affiliations The University of Melbourne, Melbourne School of Population Health, Melbourne, Victoria, Australia, Royal Children's Hospital, Murdoch Childrens Research Institute, Vaccine and Immunisation Research Group, Melbourne, Victoria, Australia

Jodie McVernon

Affiliations The University of Melbourne, Melbourne School of Population Health, Melbourne, Victoria, Australia, Royal Children's Hospital, Murdoch Childrens Research Institute, Vaccine and Immunisation Research Group, Melbourne, Victoria, Australia

Aeron C. Hurt

Affiliations WHO Collaborating Centre for Reference and Research on Influenza, Victorian Infectious Diseases Reference Laboratory, Melbourne, Victoria, Australia, Monash University, School of Applied Sciences, Churchill, Victoria, Australia

Anne Kelso

Affiliation WHO Collaborating Centre for Reference and Research on Influenza, Victorian Infectious Diseases Reference Laboratory, Melbourne, Victoria, Australia

Jennifer Mosse

Affiliation Monash University, School of Applied Sciences, Churchill, Victoria, Australia

Ian G. Barr

Affiliation WHO Collaborating Centre for Reference and Research on Influenza, Victorian Infectious Diseases Reference Laboratory, Melbourne, Victoria, Australia

Karen L. Laurie

Karen.Laurie@influenzacentre.org

Affiliations WHO Collaborating Centre for Reference and Research on Influenza, Victorian Infectious Diseases Reference Laboratory, Melbourne, Victoria, Australia, Monash University, School of Applied Sciences, Churchill, Victoria, Australia, The University of Melbourne, Department Microbiology & Immunology, Melbourne, Victoria, Australia

Competing Interests

The WHO Collaborating Centre for Reference and Research on Influenza has or has previously had collaborative agreements with the International Federation of Pharmaceutical and Manufacturers Associations, Novartis Vaccines & Diagnostics and CSL unrelated to this study. A. Kelso owns shares in CSL. J. McVernon has been a co-investigator on influenza vaccine studies sponsored by CSL, Sanofi and Novartis vaccines. She has received travel grants and honoraria from Novartis vaccines to support scientific presentations at meetings and conferences, and to sit on advisory boards. S. Maurer-Stroh, R.T.C. Lee, E. Job, S. Petrie, J.M. McCaw, and J. Mosse have no competing interests to declare. This does not alter our adherence to all PLoS Pathogens policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: T. Guarnaccia, S. Maurer-Stroh, R.T.C. Lee, P.C. Reading, J.M. McCaw, J. McVernon, I.G. Barr, K.L. Laurie. Performed the experiments: T. Guarnaccia, L.A. Carolan, S. Maurer-Stroh, R.T.C. Lee, E. Job, A.C. Hurt, K.L. Laurie. Analyzed the data: T. Guarnaccia, S. Maurer-Stroh, R.T.C. Lee, S. Petrie, J.M. McCaw, J. McVernon, A.C. Hurt, J. Mosse, K.L. Laurie. Contributed reagents/materials/analysis tools: P.C. Reading, S. Maurer-Stroh, R.T.C. Lee. Wrote the paper: T. Guranaccia, L.A. Carolan, S. Maurer-Stroh, R.T.C. Lee, E. Job, P.C. Reading, S. Petrie, J.M. McCaw, J. McVernon, A.C. Hurt, A. Kelso, J. Mosse, I.G. Barr, K.L. Laurie.