About the Authors

Deborah L. Diamond

Contributed equally to this work with: Deborah L. Diamond, Andrew J. Syder

ddiamond@u.washington.edu

Affiliation Department of Microbiology, School of Medicine, University of Washington, Seattle, Washington, United States of America

Andrew J. Syder

Contributed equally to this work with: Deborah L. Diamond, Andrew J. Syder

Current address: iTherx Pharmaceuticals, San Diego, California, United States of America

Affiliation Laboratory of Virology & Infectious Disease, Center for the Study of Hepatitis C, Rockefeller University, New York, New York, United States of America

Jon M. Jacobs

Affiliation Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, Washington, United States of America

Christina M. Sorensen

Affiliation Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, Washington, United States of America

Kathie-Anne Walters

Current address: Institute for Systems Biology, Seattle, Washington United States of America

Affiliation Department of Microbiology, School of Medicine, University of Washington, Seattle, Washington, United States of America

Sean C. Proll

Affiliation Department of Microbiology, School of Medicine, University of Washington, Seattle, Washington, United States of America

Jason E. McDermott

Affiliation Computational Biology & Bioinformatics, Pacific Northwest National Laboratory, Richland, Washington, United States of America

Marina A. Gritsenko

Affiliation Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, Washington, United States of America

Qibin Zhang

Affiliation Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, Washington, United States of America

Rui Zhao

Affiliation Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, Washington, United States of America

Thomas O. Metz

Affiliation Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, Washington, United States of America

David G. Camp II

Affiliation Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, Washington, United States of America

Katrina M. Waters

Affiliation Computational Biology & Bioinformatics, Pacific Northwest National Laboratory, Richland, Washington, United States of America

Richard D. Smith

Affiliation Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, Washington, United States of America

Charles M. Rice

Affiliation Laboratory of Virology & Infectious Disease, Center for the Study of Hepatitis C, Rockefeller University, New York, New York, United States of America

Michael G. Katze

Affiliations Department of Microbiology, School of Medicine, University of Washington, Seattle, Washington, United States of America, Washington National Primate Research Center, University of Washington Seattle, Washington, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DLD AJS JMJ KAW TOM DGC RDS CMR MGK. Performed the experiments: AJS MG QZ RZ. Analyzed the data: DLD. Contributed reagents/materials/analysis tools: DLD AJS JMJ CMS KAW SCP JEM TOM DGC KMW RDS CMR MGK. Wrote the paper: DLD AJS JMJ CMS JEM TOM CMR MGK. Processing of proteomic data: JMJ. Processing of lipidomic data: CMS TOM. Performed computational modeling: JEM KMW.