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Correction: Helios expression and Foxp3 TSDR methylation of IFNy+ and IFNy- Treg from kidney transplant recipients with good long-term graft function

  • Karina Trojan,
  • Christian Unterrainer,
  • Rolf Weimer,
  • Nuray Bulut,
  • Christian Morath,
  • Mostafa Aly,
  • Li Zhu,
  • Gerhard Opelz,
  • Volker Daniel

Correction: Helios expression and Foxp3 TSDR methylation of IFNy+ and IFNy- Treg from kidney transplant recipients with good long-term graft function

  • Karina Trojan, 
  • Christian Unterrainer, 
  • Rolf Weimer, 
  • Nuray Bulut, 
  • Christian Morath, 
  • Mostafa Aly, 
  • Li Zhu, 
  • Gerhard Opelz, 
  • Volker Daniel
PLOS
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Fig 4 is incorrect. The authors have provided a corrected version here.

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Fig 4. Methylation status of CD4+CD25+CD127-IFNγ+ Treg in transplant patients and healthy controls.

Approximately, half of male kidney transplant recipients with good long-term stable graft function show mainly methylated (>75% Foxp3 TSDR methylation) IFNy+ Treg in the blood whereas the other half of male patients possess in addition a sizeable proportion of demethylated (11–75% Foxp3 TSDR methylation) IFNy+ Treg suggesting that they possess IFNy+ Treg with transient as well as stable Foxp3 expression.

https://doi.org/10.1371/journal.pone.0179069.g001

Reference

  1. 1. Trojan K, Unterrainer C, Weimer R, Bulut N, Morath C, Aly M, et al. (2017) Helios expression and Foxp3 TSDR methylation of IFNy+ and IFNy- Treg from kidney transplant recipients with good long-term graft function. PLoS ONE 12(3): e0173773. pmid:28296931