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Correction: Middle East Respiratory Syndrome Coronavirus Intra-Host Populations Are Characterized by Numerous High Frequency Variants

  • Monica K. Borucki,
  • Victoria Lao,
  • Mona Hwang,
  • Shea Gardner,
  • Danielle Adney,
  • Vincent Munster,
  • Richard Bowen,
  • Jonathan E. Allen

Correction: Middle East Respiratory Syndrome Coronavirus Intra-Host Populations Are Characterized by Numerous High Frequency Variants

  • Monica K. Borucki, 
  • Victoria Lao, 
  • Mona Hwang, 
  • Shea Gardner, 
  • Danielle Adney, 
  • Vincent Munster, 
  • Richard Bowen, 
  • Jonathan E. Allen
PLOS
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In Table 1, the residue for 27162 should be 107, not 109. Please see the corrected Table 1 here.

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Table 1. Nonsynonymous mutations occurring at >1% at sites with at least 100 X ORP coverage.

https://doi.org/10.1371/journal.pone.0154424.t001

There is an incorrect reference to Table 1 in the second sentence of the first paragraph the Results section, “ORF1ab.” The correct sentence is: The Seed stock had iSNVs present at nts 307–313, part of the nsp1 ORF (residues 9–11). All iSNVs were detected at 4% indicating there is a second genotype present at 4%.

The incorrect value reported in Table 1 also appears in the first sentence of the Results section, “ORF5.” The correct sentence is An iSNV resulting in a stop codon at residue 107 was detected in 12% of reads at nt 27162 for camel C2D5, the only sample for which there was adequate coverage at this site (>100x, S2 Table).

Reference

  1. 1. Borucki MK, Lao V, Hwang M, Gardner S, Adney D, Munster V, et al. (2016) Middle East Respiratory Syndrome Coronavirus Intra-Host Populations Are Characterized by Numerous High Frequency Variants. PLoS ONE 11(1): e0146251. pmid:26790002