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Correction: Decreased TUSC3 Promotes Pancreatic Cancer Proliferation, Invasion and Metastasis

  • The PLOS ONE Staff

Correction: Decreased TUSC3 Promotes Pancreatic Cancer Proliferation, Invasion and Metastasis

  • The PLOS ONE Staff
PLOS
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Fig 5 appears incorrectly in the published article. Please see the complete, correct Fig 5 and its legend here. The publisher apologizes for the error.

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Fig 5. Decreased TUSC3 expression promotes tumor cell growth, migration and invasion.

(A, B) TUSC3 is effectively knocked-down in Colo357 cell lines shown by (A) RT-PCR and (B) Western blot. (C, D) Proliferation is enhanced with TUSC3 knockdown, cell number counts are significantly different at 72 hours (Colo357 TUSC3 shRNA2 vs Colo357 Scramble p = 0.0086, Colo357 TUSC3 shRNA3 vs Colo357 Scramble p = 0.0011) (D). (E, F) Colony Formation is enhanced with TSUC3 knockdown (Colo357 TUSC3 shRNA2 vs Colo357 Scramble p<0.0001, Colo357 TUSC3 shRNA3 vs Colo357 Scramble p<0.0001). (G) Migration Test (Colo357 TUSC3 shRNA2 vs Colo357 Scramble p<0.0001, Colo357 TUSC3 shRNA3 vs Colo357 Scramble p<0.0001). (H, I) Invasion Test (Colo357 TUSC3 shRNA2 vs Colo357 Scramble p<0.0001, Colo357 TUSC3 shRNA3 vs Colo357 Scramble p<0.0001). (J) Wound healing test showed more rapid closure of the gap in TUSC3 silenced cells. All experiments were performed three times with representative figures shown as above.

https://doi.org/10.1371/journal.pone.0151752.g001

Reference

  1. 1. Fan X, Zhang X, Shen J, Zhao H, Yu X, Chen Y, et al. (2016) Decreased TUSC3 Promotes Pancreatic Cancer Proliferation, Invasion and Metastasis. PLoS ONE 11(2): e0149028. pmid:26871953