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Correction: A Peptide Derived from the HIV-1 gp120 Coreceptor-Binding Region Promotes Formation of PAP248-286 Amyloid Fibrils to Enhance HIV-1 Infection

  • Jinquan Chen,
  • Ruxia Ren,
  • Suiyi Tan,
  • Wanyue Zhang,
  • Xuanxuan Zhang,
  • Fei Yu,
  • Tianrong Xun,
  • Shibo Jiang,
  • Shuwen Liu,
  • Lin Li

Correction: A Peptide Derived from the HIV-1 gp120 Coreceptor-Binding Region Promotes Formation of PAP248-286 Amyloid Fibrils to Enhance HIV-1 Infection

  • Jinquan Chen, 
  • Ruxia Ren, 
  • Suiyi Tan, 
  • Wanyue Zhang, 
  • Xuanxuan Zhang, 
  • Fei Yu, 
  • Tianrong Xun, 
  • Shibo Jiang, 
  • Shuwen Liu, 
  • Lin Li
PLOS
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Fig 7 is incorrect. The figure is incomplete. The authors have provided a new, completed version here.

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Fig 7. Schematic representation of EP2’s mechanism in promoting PAP248-286 amyloid fibril formation and enhancing HIV-1 infection.

(A) PAP248-286 amyloid fibrils enhanced HIV-1 infection. Under agitation at 37°C, PAP248-286 slowly (~ 24 h) formed amyloid fibrils, which enhanced HIV-1 infection. (B) EP2 promoted the formation of PAP248-286 amyloid fibrils. Without agitation, EP2 rapidly (~ 1 min) self-assembled into nanofibers. These nanofibers accelerated (~ 4 h) the formation of amyloid fibrils, which enhanced HIV-1 infection.

https://doi.org/10.1371/journal.pone.0147679.g001

Reference

  1. 1. Chen J, Ren R, Tan S, Zhang W, Zhang X, Yu F, et al. (2015) A Peptide Derived from the HIV-1 gp120 Coreceptor-Binding Region Promotes Formation of PAP248-286 Amyloid Fibrils to Enhance HIV-1 Infection. PLoS ONE 10(12): e0144522. pmid:26656730